I've only read through the rules so I can't say much about the gameplay just yet, but I'm really looking forward to diving in soon! I'll try to remember to come back and edit or add to this if I can.
Otherwise, the current price on this is simply too good to miss on if you're a fan of VTM or are remotely interested in it. If you're new to VTM then this might be a great gateway game (accidental alliteration) for you. A reprint / new version is coming soon-ish, and with that they've made an app for the game which will work with both versions -- score! It's in an alpha state right now according to their website, but you can check it out right now if you're interested.
Some things to consider: Amazon says the box dimensions are 14"x14"x8.5" and that it weighs 23lbs. So make sure you have the space and/or secure shelving prepared for this behemoth box!
Anywho, I think that about does it. Hope this helps someone out there!